Dead as a Dodo!

[andreoz]

Anyone with any suggestions what to check. Drove to work and noticed the engine missing a little but it came good and was running smoothly as I drove into my parking spot. In the afternoon when trying to go home - car simply would not start! All ignition lights are on and look OK, cranks beautifully but simply will not fire! Car has 165K on the clock and has not missed a beat for 16 years!
Happy to listen to any suggestions before I have it towed to a mechanic.