You will be OK on 4-5 lbs boost on a stock engine that is otherwise sound. There is a knock sensor for each bank, so if you are using the stock ECU it will modulate the [retard the] timing to suit and you will be OK.
Nobody that we know of has run 10 lbs on an unmodified engine and found it to be safe. If it ran at all I would expect it to seriously pull timing. Nobody that we know has run 10 lbs on an unmodified engine and burned out the pistons either. But then that is possibly the sort of thing that people would be slow to admit to.
If you absolutely must run 10 lbs then use water injection or water/methanol injection, that'll keep 'er cool.
Joe
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